Insulin Mouse, Alexa Fluor 488, Clone: ICBTACLS, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-9769-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15510297

Quantity Price
1 £ 80.62 / 25µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Primary or Secondary Primary
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Human, Mouse, Rat
Antigen Insulin
Isotype IgG2a
Conjugate Alexa Fluor 488
Monoclonal or Polyclonal Monoclonal
Host Species Mouse
Clone ICBTACLS
Regulatory Status RUO
Quantity 25μg
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated

This ICBTACLS monoclonal antibody reacts with the hormone insulin, responsible for regulation of carbohydrate and fat metabolism. Blood glucose levels are maintained by insulin. Insulin secretion from pancreatic beta-cells within the islets of Langerhans results in uptake of excess glucose from the blood into organs and its storage in the form of glycogen. Patients with type 1 diabetes have an autoimmune destruction of insulin-producing beta-cells in the pancreas, resulting in insulin deficiency and elevated levels of blood glucose. Patients with type 2 diabetes have insulin resistance where insulin becomes less effective at reducing the amount of blood glucose. Insulin is also important for proper endothelial cell function in with respect to vascular elasticity in response to changing blood pressure and plays a role in cognition, learning, and memory.

The ICBTACLS antibody recognizes human, mouse, and rat insulin.