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Indirubin-3'-oxime, Tocris Bioscience™

GSK-3β inhibitor. Also inhibits other protein kinases

Brand:  Tocris (Bio-Techne) 181310

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13450054

  • £139.65 / 10mg

Estimated Shipment date
from Supplier 20-11-2019

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Description

Description

Inhibitor of GSK-3β (IC50 = 190 nM) and cyclin dependent kinases (cdks; IC50 values are 0.05, 0.18 and 0.25-0.5 βM for cdk9, cdk1 and cdk2, respectively). Also reported to inhibit AMPK, LCK and SGK. Inhibits cdk5- and GSK-3β-mediated tau phosphorylation. Induces cell cycle arrest and inhibits cell proliferation.
Specifications

Chemical Identifiers

160807-49-8
277.283
indirubin-3'-monoxime, indirubin-3'-oxime, indirubin-3-oxime, indirubin-3monoxime, indirubin-3'-monooxime, indirubin-3-monoxime, 3-3-hydroxyamino-1h-indol-2-yl indol-2-one, indirubin-3′-monoxime, z-1h,1'h-2,3' biindolylidene-3,2'-dione-3-oxime, 3-1,3-dihydro-3-hydroxyimino-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one
C16H11N3O2
LDEWQRSYYHTQRA-UHFFFAOYSA-N
5326739
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NO

Specifications

10mg
160807-49-8
indirubin-3'-monoxime, indirubin-3'-oxime, indirubin-3-oxime, indirubin-3monoxime, indirubin-3'-monooxime, indirubin-3-monoxime, 3-3-hydroxyamino-1h-indol-2-yl indol-2-one, indirubin-3′-monoxime, z-1h,1'h-2,3' biindolylidene-3,2'-dione-3-oxime, 3-1,3-dihydro-3-hydroxyimino-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NO
277.283
277.28
Indirubin-3'-oxime
C16H11N3O2
LDEWQRSYYHTQRA-UHFFFAOYSA-N
3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one
5326739
>99%
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