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Indirubin-3'-oxime, Tocris Bioscience™

GSK-3β inhibitor. Also inhibits other protein kinases

Brand:  Tocris (Bio-Techne) 181350

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13460054

  • £582.37 / 50mg


Estimated Shipment
29-11-2018
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Description

Description

Protein kinase inhibitor; inhibits cyclin-dependent kinases (IC50 = 0.18 - 3.33μM) and GSK-3β (IC50 = 0.19μM). Inhibits CDK5- and GSK-3β-mediated tau phosphorylation, a process over-active in Alzheimer disease states. Also inhibits AMPK, LCK and SGK. Induces cell cycle arrest and inhibits cell proliferation.
Specifications

Chemical Identifiers

160807-49-8
277.283
indirubin-3'-monoxime, indirubin-3'-oxime, indirubin-3-oxime, indirubin-3monoxime, indirubin-3'-monooxime, indirubin-3-monoxime, 3-3-hydroxyamino-1h-indol-2-yl indol-2-one, indirubin-3′-monoxime, z-1h,1'h-2,3' biindolylidene-3,2'-dione-3-oxime, 3-1,3-dihydro-3-hydroxyimino-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one
C16H11N3O2
LDEWQRSYYHTQRA-UHFFFAOYSA-N
5326739
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NO

Specifications

Indirubin-3'-oxime
160807-49-8
indirubin-3'-monoxime, indirubin-3'-oxime, indirubin-3-oxime, indirubin-3monoxime, indirubin-3'-monooxime, indirubin-3-monoxime, 3-3-hydroxyamino-1h-indol-2-yl indol-2-one, indirubin-3′-monoxime, z-1h,1'h-2,3' biindolylidene-3,2'-dione-3-oxime, 3-1,3-dihydro-3-hydroxyimino-2h-indol-2-ylidene-1,3-dihydro-2h-indol-2-one
C1=CC=C2C(=C1)C(=C(N2)C3=C4C=CC=CC4=NC3=O)NO
277.283
277.28
50mg
C16H11N3O2
LDEWQRSYYHTQRA-UHFFFAOYSA-N
3-[3-(hydroxyamino)-1H-indol-2-yl]indol-2-one
5326739
>99%
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