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Indirubin-3'-oxime, Tocris Bioscience™

GSK-3β inhibitor. Also inhibits other protein kinases

Brand:  Tocris (Bio-Techne) 181350

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13460054

  • £608.00 / 50mg


Estimated Shipment
29-06-2018
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Description

Description

Protein kinase inhibitor; inhibits cyclin-dependent kinases (IC50 = 0.18 - 3.33μM) and GSK-3β (IC50 = 0.19μM). Inhibits CDK5- and GSK-3β-mediated tau phosphorylation, a process over-active in Alzheimer disease states. Also inhibits AMPK, LCK and SGK. Induces cell cycle arrest and inhibits cell proliferation.
Specifications

Chemical Identifiers

Indirubin-3'-oxime
C16H11N3O2
277.28
3-[1, 3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1, 3-dihydro-2H-indol-2-one

Specifications

Indirubin-3'-oxime
>99%
277.28
50mg
160807-49-8
C16H11N3O2
3-[1, 3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1, 3-dihydro-2H-indol-2-one
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