IL-9 Mouse anti-Human, eFluor 660, Clone: MH9A4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-7097-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15520017

Quantity Price
1 £ 78.88 / 25 tests
Estimated Shipment date
from Supplier 05-05-2017
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Description and Specification

Specification

Quantity 25 tests
Applications Flow Cytometry
Applications Flow Cytometry (Intracellular Staining)
Clone MH9A4
Host Species Mouse
Conjugate eFluor 660
Isotype IgG2b
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Concentration 5μL (0.06μg)/test
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Regulatory Status RUO
Species Reactivity Human
Antigen IL-9
Monoclonal or Polyclonal Monoclonal
Gene Alias Interleukin-9
Format Conjugated

The monoclonal antibody MH9A4 recognizes interleukin-9 (IL-9), a proinflammatory cytokine historically believed to be involved in type 2 immune responses. Recent evidence suggests IL-9 may instead be secreted by a distinct T-helper lineage called Th9. These cells can be derived from Th2 cells with TGF beta or differentiated directly from naïve CD4+ T cells with TGF beta and IL-4.

IL-9 is a member of the common cytokine receptor gamma chain-dependent family of cytokines which also includes IL-2, IL-4, IL-7, IL-15 and IL-21. Its pleiotropic effects on Th2 lymphocytes, B lymphocytes, mast cells, eosinophils and gut and airway epithelial cells have implicated IL-9 in asthma and other allergy-related disorders. Staining with the MH9A4 antibody is not blocked by the MH9D1 antibody, suggesting that the two antibodies bind to unique epitopes.