IL-9 Mouse anti-Human, eFluor 660, Clone: MH9A4, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 50-7097-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15530017

Quantity Price
1 £ 182.82 / 100 tests
Estimated Shipment date
from Supplier 03-05-2017
Add to basket


Description and Specification

Specification

Concentration 5μL (0.06μg)/test
Conjugate eFluor 660
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Applications Flow Cytometry (Intracellular Staining)
Isotype IgG2b
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100 tests
Format Conjugated
Clone MH9A4
Host Species Mouse
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Gene Alias Interleukin-9
Primary or Secondary Primary
Antigen IL-9
Species Reactivity Human

The monoclonal antibody MH9A4 recognizes interleukin-9 (IL-9), a proinflammatory cytokine historically believed to be involved in type 2 immune responses. Recent evidence suggests IL-9 may instead be secreted by a distinct T-helper lineage called Th9. These cells can be derived from Th2 cells with TGF beta or differentiated directly from naïve CD4+ T cells with TGF beta and IL-4.

IL-9 is a member of the common cytokine receptor gamma chain-dependent family of cytokines which also includes IL-2, IL-4, IL-7, IL-15 and IL-21. Its pleiotropic effects on Th2 lymphocytes, B lymphocytes, mast cells, eosinophils and gut and airway epithelial cells have implicated IL-9 in asthma and other allergy-related disorders. Staining with the MH9A4 antibody is not blocked by the MH9D1 antibody, suggesting that the two antibodies bind to unique epitopes.