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IL-8 (1-77) (CXCL8) Monoclonal Antibody (8CH), eFluor™ 450, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

£90.75 - £239.00

Specifications

Antigen IL-8 (1-77) (CXCL8)
Clone 8CH
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Product Code Brand Quantity Price Quantity & Availability  
15599816
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Affymetrix eBioscience
48-8088-42
100 Tests
£239.00
100 tests
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15589816
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Affymetrix eBioscience
48-8088-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: This 8CH monoclonal antibody reacts with human IL-8 (CXCL8), a pro-inflammatory CXC chemokine. It is synthesized as a 99 amino acid precursor protein that is further processed into one of four isoforms, with the most common being 72 or 77 amino acids in length. IL-8(77) is secreted primarily by endothelial cells and is thought to be a less potent neutrophil activator than the other forms. It is present at high levels during fetal development, where it mediates angiogenesis rather than inflammation. The predomit form present in adults is IL-8(72), which is expressed by monocytes, macrophages, epithelial cells, and fibroblasts in response to inflammatory stimuli, environmental stress, and steroid hormones. IL-8(72) is essential for the activation and recruitment of neutrophils to sites of inflammation, and has also been found to influence T cell migration. Signaling occurs through the G-protein coupled receptors CXCR1 or CXCR2. IL-8 transcripts are often upregulated in tumors, and it is associated with tumor angiogenesis and metastasis. Applications Reported: This 8CH antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This 8CH antibody has been pre-titrated and tested by intracellular staining followed by flow cytometric analysis. This can be used at 5 μL (0.06 μg) per test.

IL-8 (1-77) (CXCL8) Monoclonal antibody specifically detects IL-8 (1-77) (CXCL8) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

IL-8 (1-77) (CXCL8)
5 μL/Test
Monoclonal
Liquid
RUO
P10145
CXCL8
Primary
4° C, store in dark, DO NOT FREEZE!
CXCL8
8CH
Flow Cytometry
eFluor 450
Mouse
Human
3576
IgG1 κ
Affinity chromatography
Antibody
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