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IL-8 (CXCL8) Mouse anti-Human, Clone: N11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-7189-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15288037

  • £164.47 / 100µg


Estimated Shipment
03-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody N11 reacts specifically with the 77 amino acid form of IL-8 (IL-877, IL-8(1-77), CXCL877) and does not react with the more common 72 amino acid form. Frequently referred to as “endothelial” IL-8, the 77 amino acid form is secreted in cultured leukocytes. The 72 amino acid form is the result of efficient cleavage of an N-terminal pentamer from IL-877 after secretion. IL-8 is a C-X-C chemokine with potency in neutrophil chemotaxis and activation. IL-877 has decreased chemotactic activity when compared to IL-872, but has other specific pro-apoptotic and tumor cell chemotactic activities. IL-877 has recently been shown to be the major isoform present in premature neonates due to deficiency in serum protease activity that is not seen in term neonates.
Description & Specifications

Specifications

IL-8 (CXCL8)
N11
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
Purified
Interleukin-8, IL8
IgG1
RUO
Primary
Human