IL-8 (CXCL8) Mouse anti-Human, Clone: N11, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-7189-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15288037

Quantity Price
1 £ 164.47 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification


Species Reactivity Human
Primary or Secondary Primary
Applications Western Blotting
Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Gene Alias Interleukin-8, IL8
Conjugate Unlabeled
Clone N11
Isotype IgG1
Quantity 100μg
Format Purified
Regulatory Status RUO
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Host Species Mouse
Antigen IL-8 (CXCL8)

The monoclonal antibody N11 reacts specifically with the 77 amino acid form of IL-8 (IL-877, IL-8(1-77), CXCL877) and does not react with the more common 72 amino acid form. Frequently referred to as “endothelial” IL-8, the 77 amino acid form is secreted in cultured leukocytes. The 72 amino acid form is the result of efficient cleavage of an N-terminal pentamer from IL-877 after secretion. IL-8 is a C-X-C chemokine with potency in neutrophil chemotaxis and activation. IL-877 has decreased chemotactic activity when compared to IL-872, but has other specific pro-apoptotic and tumor cell chemotactic activities. IL-877 has recently been shown to be the major isoform present in premature neonates due to deficiency in serum protease activity that is not seen in term neonates.