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IL-4 Monoclonal Antibody (BVD6-24G2), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£219.00

Specifications

Antigen IL-4
Clone BVD6-24G2
Concentration 0.5 mg/mL
Classification Monoclonal
Conjugate Biotin
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Products 1
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15320020
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Affymetrix eBioscience
13-7042-85
500 μg
£219.00
500µg
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Estimated Shipment: 12-04-2024
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Description

Description

Description: The BVD6-24G2 antibody reacts with mouse interleukin-4 (IL-4), a 14 kDa cytokine secreted by Th2 cells. Applications Reported: The BVD6-24G2 antibody is used for detection of mouse IL-4 by ELISA. Applications Tested: The BVD6-24G2 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of mouse Interleukin-4 (IL-4) in combination with the purified 11B11 (14-7041) antibody for capture and recombinant mouse IL-4 (14-8041) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 500 pg/mL - 4 pg/mL should be included in each ELISA plate. Filtration: 0.2 μm post-manufacturing filtered.

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Specifications

Specifications

IL-4
0.5 mg/mL
Biotin
Rat
Mouse
16189
IgG1 κ
Affinity chromatography
Antibody
BVD6-24G2
Monoclonal
Liquid
RUO
P07750
Il4
Primary
4° C, store in dark, DO NOT FREEZE!
Il4
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