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IL-4 Monoclonal Antibody (BVD6-24G2), Biotin, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
£219.00
Specifications
Antigen | IL-4 |
---|---|
Clone | BVD6-24G2 |
Concentration | 0.5 mg/mL |
Classification | Monoclonal |
Conjugate | Biotin |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15320020
|
Affymetrix eBioscience
13-7042-85 |
500 μg |
£219.00
500µg |
Estimated Shipment: 12-04-2024 Log in to see stock. |
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Description
Description: The BVD6-24G2 antibody reacts with mouse interleukin-4 (IL-4), a 14 kDa cytokine secreted by Th2 cells. Applications Reported: The BVD6-24G2 antibody is used for detection of mouse IL-4 by ELISA. Applications Tested: The BVD6-24G2 antibody has been tested as the detection antibody in a sandwich ELISA for analysis of mouse Interleukin-4 (IL-4) in combination with the purified 11B11 (14-7041) antibody for capture and recombinant mouse IL-4 (14-8041) as the standard. A suitable range of concentrations of this antibody for ELISA detection is 0.5-2 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 500 pg/mL - 4 pg/mL should be included in each ELISA plate. Filtration: 0.2 μm post-manufacturing filtered.
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.Specifications
IL-4 | |
0.5 mg/mL | |
Biotin | |
Rat | |
Mouse | |
16189 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
BVD6-24G2 | |
Monoclonal | |
Liquid | |
RUO | |
P07750 | |
Il4 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Il4 |
For Research Use Only.