IL-4 Mouse anti-Rat, Clone: OX81, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-7045-85

500UG Anti-Rat IL-4 Functional Grade Purified

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15527806

Quantity Price
1 £ 325.2 / 500µg
Estimated Shipment date
from Supplier 09-12-2016
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Description and Specification

Specification

Antigen IL-4
Applications Flow Cytometry (Intracellular Staining)
Applications Functional Assay
Applications Western Blotting
Clone OX81
Concentration 1mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias Interleukin-4
Host Species Mouse
Isotype IgG1
Quantity 500μg
Regulatory Status RUO
Species Reactivity Rat
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This OX81 monoclonal antibody reacts with rat interleukin (IL)-4. Also known as BCDF, BCGF-1 and BSF-1, IL-4 is secreted by activated Th2 and natural killer T cells. This cytokine is also produced by Th1 and mast cells albeit to a lesser extent. IL-4 is species-specific and promotes proliferation and differentiation of B cells. IL-4, in conjunction with other signals such as CD40, induces Ig isotype switching of B cells and the upregulation of MHC class II and CD23.

The OX81 antibody has been reported to exhibit neutralizing activity.