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IL-38, eFluor 660, clone: H127C, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-7385-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15510047

  • £189.15 / 100µg


Estimated Shipment date
from Supplier 25-05-2018
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Description

Description

Description: The monoclonal antibody H127C recognizes human IL-38. IL-38 is a member of the Interleukin-1 family (IL-1F) and shares homology with IL-1R antagonist (IL-1Ra) and IL-36R antagonist (IL-36Ra). IL-38 is expressed mostly in the skin and proliferating B cells of the tonsil and is also present at low levels in the heart and placenta. IL-38 functions as an anti-inflammatory cytokine that inhibits IL-36 by binding to IL-36R and also inhibits the production of IL-17 and IL-22. Gene polymorphisms of IL-38 are associated with psoriatic arthritis, ankylosing spondylitis, and heart disease.Applications Reported: This H127C antibody has been reported for use in immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This H127C antibody has been tested tested by immunohistochemistry on human FFPE tissue using low pH antigen retrieval and can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.eFluor® 660 is a replacement for Alexa Fluor® 647. eFluor® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome.Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-38
Monoclonal
0.2mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q8WWZ1
IL-38, FKSG75, IL1HY2, IL-1HY2, IL1-theta, FIL1-theta, FIL1T, IL38, UNQ6119/PRO20041, Interleukin-1 family member 10, Family of interleukin 1-theta, IL-1F10
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry
H127C
eFluor 660
IL1F10
Conjugated
IL1F10
IgG2b, kappa
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
84639
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