IL-38, clone: H127C, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-7385-80
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionDescription: The monoclonal antibody H127C recognizes human IL-38. IL-38 is a member of the Interleukin-1 family (IL-1F) and shares homology with IL-1R antagonist (IL-1Ra) and IL-36R antagonist (IL-36Ra). IL-38 is expressed mostly in the skin and proliferating B cells of the tonsil and is also present at low levels in the heart and placenta. IL-38 functions as an anti-inflammatory cytokine that inhibits IL-36 by binding to IL-36R and also inhibits the production of IL-17 and IL-22. Gene polymorphisms of IL-38 are associated with psoriatic arthritis, ankylosing spondylitis, and heart disease.Applications Reported: This H127C antibody has been reported for use in flow cytometric analysis, immunoprecipitation, western blotting, ELISA, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections.Applications Tested: This H127C antibody has been tested by immunohistochemistry on formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 0.1 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|Store at 2-8°C.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|