IL-38 Mouse anti-Human, Biotin, Clone: H127C, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 13-7385-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15527356

Quantity Price
1 £ 176.7 / 100µg
Estimated Shipment date
from Supplier 08-05-2017
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Description and Specification

Specification

Format Conjugated
Gene Alias Interleukin-38, IL-1F10
Primary or Secondary Primary
Regulatory Status RUO
Isotype IgG2b
Monoclonal or Polyclonal Monoclonal
Applications Immunohistochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Storage Requirements Store at 2-8°C. Do not freeze.
Concentration 0.5mg/mL
Host Species Mouse
Clone H127C
Quantity 100μg
Conjugate Biotin
Antigen IL-38
Species Reactivity Human
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The monoclonal antibody H127C recognizes human IL-38. IL-38 is a member of the Interleukin-1 family (IL-1F) and shares homology with IL-1R antagonist (IL-1Ra) and IL-36R antagonist (IL-36Ra). IL-38 is expressed mostly in the skin and proliferating B cells of the tonsil and is also present at low levels in the heart and placenta. IL-38 functions as an anti-inflammatory cytokine that inhibits IL-36 by binding to IL-36R and also inhibits the production of IL-17 and IL-22. Gene polymorphisms of IL-38 are associated with psoriatic arthritis, ankylosing spondylitis, and heart disease.