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IL-33R (ST2) Rat anti-Mouse, PE, Clone: RMST2-33, eBioscience™

Rat Monoclonal Antibody

£85.25 - £203.00

Specifications

Antigen IL-33R (ST2)
Clone RMST2-33
Target Species Mouse
Conjugate PE
Isotype IgG2b, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15567196
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Affymetrix eBioscience
12-9333-80
25 μg £85.25
25µg View alternative products
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Estimated Shipment
03-11-2020
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15577196
View Documents
Affymetrix eBioscience
12-9333-82
100 μg £203.00
100µg View alternative products
Save Up to 
»
Estimated Shipment
02-11-2020
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Description

Description

ST2 is a member of the interleukin 1 receptor family. Studies of ST2 in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. ST2 belongs to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. ST2 is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Reports also suggest its possible role in helper T-cell function as well as in cell growth. Three isoforms of ST2 have been reported where isoform C is a membrane form and isoform B is a secreted form. ST2 may be induced by proinflammatory stimuli, and may also be found in serum of autoimmune disease. Different isoforms are restricted to different tissues while high expression of this protein is evident in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine.
Specifications

Specifications

IL-33R (ST2)
Mouse
IgG2b, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
RMST2-33
PE
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.