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IL-33R (ST2), PE, clone: RMST2-33, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9333-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15577196

  • £193.08 / 100µg


EU Stock 1
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Description

Description

Description: The RMST2-33 monoclonal antibody reacts with mouse ST2, also known as IL-33R or interleukin 1 receptor-like 1. ST2 is a member of the IL-1 receptor family. In the membrane-bound form, it consists of three extracellular immunoglobulin domains and an intracellular toll-interleukin-1 receptor domain. ST2 forms a dimer with IL-1R accessory protein in a ligand-dependent manner. IL-33/ST2 interaction induces the production of TH2 cytokines. ST2 also has a soluble isoform lacking transmembrane and intracellular toll-interleukin-1 receptor domains. It is believed that the soluble form functions as a decoy receptor that can block membrane bound IL-33/ST2 interaction. ST2 is expressed by TH2 lymphocytes, mast cells, eosinophils, basophils, innate lymphocytes, smooth muscle cells, and endothelial cells and is involved in host defense, allergy, and inflammation. IL-33/ST2 interaction has also been shown to be atheroprotective.RMST2-33 has been reported to bind and activate ST2 in in vitro assays.Applications Reported: This RMST2-33 antibody has been reported for use in flow cytometric analysis.Applications Tested: This RMST2-33 antibody has been tested by flow cytometric analysis of mouse bone marrow-derived mast cells.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-33R (ST2)
Monoclonal
0.2mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P14719
DER4, Fit-1, Ly84, ST2L, St2, St2-rs1, T1, T1/ST2
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
RMST2-33
PE
Il1rl1
Conjugated
Il1rl1
IgG2b, kappa
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
17082
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