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IL-33R (ST2) Rat anti-Mouse, Biotin, Clone: RMST2-2, eBioscience™

Rat Monoclonal Antibody

£52.50 - £120.00

Specifications

Antigen IL-33R (ST2)
Clone RMST2-2
Target Species Mouse
Conjugate Biotin
Isotype IgG2a, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15587356 View Documents Affymetrix eBioscience
13-9335-80
25 μg £52.50
25µg View alternative products
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Estimated Shipment date
from Supplier 15-05-2020
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15597356 View Documents Affymetrix eBioscience
13-9335-82
100 μg £120.00
100µg View alternative products
Save Up to 
»
Estimated Shipment date
from Supplier 17-04-2020
Please to purchase this item. Need a web account? Register with us today!
Description

Description

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered. ST2 is a member of the interleukin 1 receptor family. Studies of ST2 in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. ST2 belongs to the interleukin-1 receptor family with three Ig-like C2-type (immunoglobulin-like) domains and a TIR domain. ST2 is a receptor for interleukin-33 (IL-33) which upon stimulation recruits the signaling molecules MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Reports also suggest its possible role in helper T-cell function as well as in cell growth. Three isoforms of ST2 have been reported where isoform C is a membrane form and isoform B is a secreted form. ST2 may be induced by proinflammatory stimuli, and may also be found in serum of autoimmune disease. Different isoforms are restricted to different tissues while high expression of this protein is evident in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine.
Specifications

Specifications

IL-33R (ST2)
Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
RMST2-2
Biotin
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.