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IL-33R (ST2) Monoclonal Antibody (RMST2-2), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£110.00 - £258.00

Specifications

Antigen IL-33R (ST2)
Clone RMST2-2
Concentration 0.5 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15590267
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Affymetrix eBioscience
53-9335-80
25 μg
£110.00
25µg
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Estimated Shipment: 07-05-2024
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15500277
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Affymetrix eBioscience
53-9335-82
100 μg
£258.00
100µg
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Estimated Shipment: 08-04-2024
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Description

Description

Description: The RMST2-2 monoclonal antibody reacts with ST2, also known as IL-33 receptor (IL-33R) or interleukin 1 receptor-like 1. ST2 is a member of the IL-1 receptor family. In the membrane-bound form, it consists of three extra-cellular immunoglobulin domains and an intracellular toll-interleukin-1 receptor domain. ST2 forms a dimer with IL-1R accessory protein in a ligand-dependent manner. The IL-33/ST2 interaction induces the production of TH2 cytokines. ST2 also has a soluble isoform lacking transmembrane and intracellular toll-interleukin-1 receptor domains. It is believed that the soluble form functions as a decoy receptor that can block membrane bound IL-33/ST2 interaction. ST2 is expressed by TH2 lymphocytes, mast cells, eosinophils, basophils, innate lymphocytes, smooth muscle cells, and endothelial cells and is involved in host defense, allergy, and inflammation. The IL-33/ST2 interaction has also been shown to be atheroprotective. Applications Reported: This RMST2-2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This RMST2-2 antibody has been tested by flow cytometric analysis of mouse bone marrow-derived mast cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

IL-33R (ST2) Monoclonal antibody specifically detects IL-33R (ST2) in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

IL-33R (ST2)
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2
IL1RL1
Primary
4° C, store in dark, DO NOT FREEZE!
IL1RL1
RMST2-2
Flow Cytometry
Alexa Fluor 488
Rat
Mouse
P14719
17082
IgG2a κ
Affinity chromatography
Antibody
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