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IL-22 Monoclonal Antibody (1H8PWSR), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 46-7221-80

108.67 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15351390

  • £163.00 / 25µg
Estimated Shipment: 26-03-2024
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Description

Description

Description: The 1H8PWSR monoclonal antibody reacts with mouse interleukin(IL)-22. IL-22 is a 20 kDa member of the IL-10 cytokine family that is secreted primarily by Th17, NK cells, and some other T cells. In in vitro Th17 cultures, induction of IL-22 expression is greater in response to IL-23 than IL-6 or TGF-β, suggesting that this cytokine may be secreted by more fully differentiated Th17 cells in vivo. A heterodimer consisting of IL-10R2 and IL-22R1 serves as the receptor for IL-22. Th17-secreted IL-22 binds to the IL-22 receptor complexon target cells to induce the expression of anti-microbial peptides β-defensin-2 and β-defensin-3. Recently, it was demonstrated that IL-22 is able to protect hosts against bacterial infections of the lungs and gut. Applications Reported: This 1H8PWSR antibody has been reported for use in intracellular staining followed by flow cytometric analysis. This clone has been optimized for use with eBioscience IC Fixation and Permeabilization kit (cat. 88-8823). Applications Tested: This 1H8PWSR antibody has been tested on Th17-polarized mouse splenocytes restimulated with PMA, Ionomycin and Brefeldin A for 5 hours. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

IL-22 Monoclonal antibody specifically detects IL-22 in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

IL-22
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q9JJY9
IL22
Affinity chromatography
RUO
50929
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
1H8PWSR
PerCP-eFluor 710
IL22
Cytokine Zcyto18; EGK_03903; il 22; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL22; IL-22; Il22a; IL-22a; IL-D110; ILN; ILTIF; IL-TIF; ILTIF alpha; IL-TIF alpha; ILTIFa; Interleukin; interleukin 10-related T cell-derived inducible factor; interleukin 22; Interleukin22; interleukin-22; Interleukin-22a; RGD1561292; TIFa; TIFIL-23; UNQ3099/PRO10096; ZCYTO18
Rat
25 μg
Primary
Mouse
Antibody
IgG1 κ
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For Research Use Only.