missing translation for 'onlineSavingsMsg'
Learn More

IL-22 Rat anti-Human, Mouse, APC, Clone: IL22JOP, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-7222-80

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

 View more versions of this product

Product Code. 15320840

  • £86.73 / 25µg


EU Stock 8
Add to basket

Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody IL22JOP reacts with and inhibits the bioactivity of human and mouse IL-22. IL-22 is a 20kDa member of the IL-10 cytokine family that is secreted primarily by Th17 cells, NK cells, and other T cells. Compared to IL-6 or TGF-β, IL-23 can induce greater levels of IL-22 in in vitro-differentiated Th17 cells. This observation suggests that IL-22 may be secreted by more fully differentiated Th17 cells in vivo. Recently, it was demonstrated that IL-22 could protect hosts from bacterial infection of the lungs and gut. Moreover, it has been reported that anti-CD3/CD28-induced production of IL-22 by PBMCs was elevated significantly in asthma patients compared to control patients. Flow cytometric analysis also showed that the frequencies of IL-17+IL-22+ CD4 T cells were increased in PBMCs from patients with ankylosing spondylitis and rheumatoid arthritis.
Description & Specifications

Specifications

IL-22
IL22JOP
Allophycocyanin
Conjugated
Rat
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-22, IL22
IgG2a
RUO
Primary
Murine