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IL-20 Receptor 2 Rat anti-Human, Mouse, Clone: 20RNTC, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1206-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15287187

  • £140.02 / 100µg


Estimated Shipment
08-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi.
Description & Specifications

Specifications

IL-20 Receptor 2
20RNTC
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
Purified
Interleukin-20 Receptor
IgG2a
RUO
Primary
Murine