IL-20 Receptor 2 Rat anti-Human, Mouse, Clone: 20RNTC, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1206-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15287187

Quantity Price
1 £ 140.02 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Quantity 100μg
Primary or Secondary Primary
Applications Flow Cytometry
Applications Immunocytochemistry
Applications Western Blotting
Regulatory Status RUO
Isotype IgG2a
Format Purified
Monoclonal or Polyclonal Monoclonal
Host Species Rat
Clone 20RNTC
Concentration 0.5mg/mL
Gene Alias Interleukin-20 Receptor
Antigen IL-20 Receptor 2
Storage Requirements Store at 2-8°C.
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Conjugate Unlabeled
Species Reactivity Human, Mouse

This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi.