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IL-2 Monoclonal Antibody (JES6-5H4), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£115.00 - £199.00

Specifications

Antigen IL-2
Clone JES6-5H4
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15299269
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Affymetrix eBioscience
12-7021-81
50 μg
£115.00
50µg
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Estimated Shipment: 10-04-2024
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15209279
View Documents Promotion Details
Affymetrix eBioscience
12-7021-82
100 μg
£199.00
100µg
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»
Estimated Shipment: 10-04-2024
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Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The JES6-5H4 antibody reacts with mouse interleukin-2 (IL-2), a 17 kDa T cell growth factor and a major immunoregulatory cytokine. Applications Reported: JES6-5H4 has been reported for use in intracellular flow cytometric analysis. Applications Tested: This JES6-5H4 antibody is offered in 2 formats: - μg size: has been tested ny intracellular staining of 6-hour PMA and Ionomycin-activated mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. - test size: has been pre-titrated and tested ny intracellular staining of 6-hour PMA and Ionomycin-activated mouse splenocytes. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an μgcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
Specifications

Specifications

IL-2
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
aldesleukin; cytokine; H-IL-2; il 2; Il2; Il-2; ILN; Interleukin; interleukin 2; interleukin 2 precursor; interleukin 2 variant IL2delta2; Interleukin2; Interleukin-2; interleukin-2 precursor; interleukin-2 precursor protein; interleukin-2; interleukin 2; Involved in regulation of T cell clonal expansion; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; patial sequence of Interleukin-2; POIL2; porcine Interleukin 2; T cell growth factor; T-cell growth factor; T-cell growth factor (TCGF); TCGF
IL2
Primary
4° C, store in dark, DO NOT FREEZE!
IL2
JES6-5H4
Flow Cytometry
PE
Rat
Mouse
P04351
16183
IgG2b κ
Affinity chromatography
Antibody
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