IL-2 Rat anti-Mouse, Clone: JES6-1A12, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-7022-95

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15597796

Quantity Price
1 £ 1527.92 / 10mg
Estimated Shipment date
from Supplier 02-05-2017
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Description and Specification

Specification

Quantity 10mg
Formulation aqueous buffer, no sodium azide
Applications Cytokine Neutralization
Applications ELISA Capture
Applications ELISPOT
Applications Immunoprecipitation
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Isotype IgG2a
Antigen IL-2
Clone JES6-1A12
Gene Alias Interleukin-2
Conjugate Unlabeled
Concentration 1mg/mL
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Format Purified
Host Species Rat

The JES6-1A12 antibody reacts with mouse interleukin-2 (IL-2). The JES6-1A12 antibody is a neutralizing antibody. Mouse IL-2 (also known as TCGF) is a 17kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.