IL-2 Rat anti-Mouse, Clone: JES6-1A12, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-7022-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298737

Quantity Price
1 £ 54.42 / 50µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Concentration 1mg/mL
Host Species Rat
Isotype IgG2a
Applications Cytokine Neutralization
Applications ELISA Capture
Applications ELISPOT
Applications Immunoprecipitation
Species Reactivity Mouse
Conjugate Unlabeled
Quantity 50μg
Gene Alias Interleukin-2
Antigen IL-2
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Clone JES6-1A12
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Regulatory Status RUO
Format Purified

The JES6-1A12 antibody reacts with mouse interleukin-2 (IL-2). The JES6-1A12 antibody is a neutralizing antibody. Mouse IL-2 (also known as TCGF) is a 17kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.