missing translation for 'onlineSavingsMsg'
Learn More

IL-2, clone: JES6-1A12, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-7022-85

Code : Z2

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15227987

  • £145.28 / 500µg


EU Stock 3
Add to basket

Description

Description

Description: The JES6-1A12 antibody reacts with mouse interleukin-2 (IL-2). The JES6-1A12 antibody is a neutralizing antibody. Mouse IL-2 (also known as TCGF) is a 17kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.Applications Reported: The JES6-1A12 antibody has been reported for use in ELISA capture, ELISPOT capture, neutralization of IL-2 bioactivity, IP, and intracellular staining.Applications Tested: The JES6-1A12 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse Interleukin-2 (IL-2) in combination with the biotin JES6-5H4 (13-7021) antibody for detection and recombinant mouse IL-2 (14-8021) as the standard. A suitable range of concentrations of this antibody for ELISA capture is 1-4 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 500 pg/mL - 4 pg/mL should be included in each ELISA plate.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-2
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P04351
Interleukin-2, T-cell growth factor, TCGF, Aldesleukin
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
ELISAþDot blotþImmunoprecipitation
JES6-1A12
Unconjugated
Il2
Purified
Il2
IgG2a, kappa
500μg
Store at 2-8°C.
Primary
16183
Videos

For Research Use Only.