missing translation for 'onlineSavingsMsg'
Learn More

IL-17F Rat anti-Human, eFluor 450, Clone: SHLR17, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-7169-41

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15579806

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance
View alternative products »

Disclaimers:

For Research Use Only.


Description

Description

The SHLR17 monoclonal antibody reacts with human interleukin (IL)-17F. IL-17F is a homodimeric, 34kDa member of the IL-17 family, which includes IL-17(A), B, C, D, E (IL-25). Within this family, IL-17A and IL-17F are produced preferentially by T helper 17 (Th17) cells, with other members produced more widely. IL-17F and IL-17A have many overlapping functions, but knockout studies have shown each to have independent functions as well. In vitro cultured Th17 cells have been shown to express IL-17F and IL-17A homodimers and IL-17A/F heterodimers depending on the culture conditions and their differentiation state. A heterodimer of IL-17RA and IL-17RC has been shown to bind IL-17F, resulting in target cell-secretion of pro-inflammatory cytokines and chemokines, as well as neutrophil recruitment.
Specifications

Specifications

IL-17F
SHLR17
eFluor 450
Conjugated
Rat
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-17F
IgG1
RUO
Primary
Human
Videos
Alternative Products