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IL-17AF Mouse anti-Human, PE, Clone: 20LJS09, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9179-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15547186

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Disclaimers:

For Research Use Only.


Description

Description

The 20LJS09 monoclonal antibody reacts with human interleukin (IL)-17AF heterodimer. This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers. IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells. Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF. Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.
Specifications

Specifications

IL-17AF
20LJS09
PE
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.5μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-17AF
IgG1
RUO
Primary
Human
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