missing translation for 'onlineSavingsMsg'
Learn More

IL-17AF, PE, clone: 20LJS09, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9179-42

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15557186

  • £230.92 / 100 tests


EU Stock 4
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

Description: The 20LJS09 monoclonal antibody reacts with human interleukin (IL)-17AF heterodimer. This antibody specifically reacts with this heterodimer and has no reactivity for IL-17A or IL-17F homodimers. IL-17A and IL-17F are well-characterized homodimeric cytokines secreted by T helper 17 (Th17) cells, gamma-delta T cells and several subsets of innate lymphoid cells. Somewhat less appreciated, IL-17A and IL-17F subunits can also form the heterodimer, IL-17AF. Together, these three dimers signal through the IL-17RA/IL-17RC receptor complex to mediate immune responses at mucosal interfaces and are found at lesion sites in inflammatory bowel disease, asthma, atopic dermatitis and rheumatoid arthritis.Applications Reported: This 20LJS09 antibody has been reported for use in intracellular staining followed by flow cytometric analysis.Applications Tested: This 20LJS09 antibody has been pre-titrated and tested on 10 day in vitro-polarized Th17 cells. This can be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-17AF
20LJS09
PE
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry (Intracellular Staining)
5μL (0.5μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-17AF
IgG1
RUO
Primary
Human
Videos