IL-15 Rat anti-Mouse, Clone: AIO.3, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-7154-38

Product Code. 15507816

Disclaimers:

For Research Use Only.

Description

The AIO.3 antibody reacts with mouse IL-15. This is a neutralizing antibody. Mouse IL-15 is a 14-15kDa factor, previously known as IL-T. IL-15 is produced by a variety of cells and has a role in the T cell-mediated immune response and the central nervous system. IL-15 binds to the β and γ subunits of the IL-2 receptor; however, these two cytokines have distinct biological activities. IL-15 is a specific maturation factor for NK cells and mimics the BM microenvironment for NK cell development in vitro. It is reported that IL-15 delivers an anti-apoptotic and survival signal for NK, T, and B cells.

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Specifications

• Antigen: IL-15
• Clone: AIO.3
• Conjugate: Unlabeled
• Formulation: aqueous buffer, no sodium azide
• Host Species: Rat
• Quantity: 5mg
• Storage Requirements: Store at 2-8°C.
• Monoclonal or Polyclonal: Monoclonal

• Applications: Functional Assay
• Concentration: 1mg/mL
• Format: Purified
• Gene Alias: Interleukin-15, IL15
• Isotype: IgG2a
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Murine