missing translation for 'onlineSavingsMsg'
Learn More

IL-13 Monoclonal Antibody (eBio13A), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

£81.00 - £215.00

Specifications

Antigen IL-13
Clone eBio13A
Applications Flow Cytometry
Classification Monoclonal
Conjugate PE
View More Specs

Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15249299
View Documents Promotion Details
Affymetrix eBioscience
12-7133-81
50 μg
£125.00
50µg
View alternative products
Save Up to 
»
Estimated Shipment: 09-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
15259299
View Documents Promotion Details
Affymetrix eBioscience
12-7133-82
100 μg
£215.00
100µg
View alternative products
Save Up to 
»
In Stock
to see stock.
Please to purchase this item. Need a web account? Register with us today!
15567096
View Documents Promotion Details
Affymetrix eBioscience
12-7133-41
25 Tests
£81.00
25 tests
View alternative products
Save Up to 
»
Estimated Shipment: 10-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The eBio13A antibody reacts with mouse IL-13. IL-13 is a cytokine produced mainly by Th2 cells, but also by antigen-primed CD8 T cells. IL-13 has a strong involvement in allergic inflammation and parasitic clearing and in cancer models has been shown to have either inhibitory or stimulatory activity depending on the tumor. In humans, IL-13 is found to play a role in isotype switching in B cells. IL-13 is implicating in down modulating macrophage activity, through the reduction of pro-inflammatory cytokines (IL-1, IL-6, IL-8, IL-10, IL-12) Applications Reported: The eBio13A antibody has been reported useful for ELISA and ELISPOT capture, as well as intracellular staining for flow cytometric analysis. Applications Tested: This eBio13A antibody is tested intracellular staining of cultured mouse splenocytes. It is offered in 2 formats: - μg size: has been tested intracellular staining of cultured mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. - test size: has been pre-titrated and tested intracellular staining of cultured mouse splenocytes. This can be used at 5 μL (0.125 μg) per test.

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
Specifications

Specifications

IL-13
Flow Cytometry
PE
Rat
Mouse
ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
Il13
Primary
4° C, store in dark, DO NOT FREEZE!
Il13
eBio13A
Monoclonal
Liquid
RUO
P20109
16163
IgG1 κ
Affinity chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.