missing translation for 'onlineSavingsMsg'
Learn More

IL-13 Rat anti-Mouse, Clone: eBio1316H, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Brand:  Affymetrix eBioscience 16-7135-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15278767

  • £54.42 / 50µg


Call for latest availability
+44 (0)1509 555 500
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

The eBio1316H antibody reacts with mouse IL-13. The eBio1316H antibody is a neutralizing antibody. Mouse interleukin-13 (IL-13), originally designated p600, is a 11.6kDa protein secreted by activated T helper cells, CD8+ T cells, and NK cells. IL-13 was originally identified in 1989 through differential hybridization of cDNA libraries prepared from T helper 1 and T helper 2 cells. IL-13 contains four cysteine residues, which form two intramolecular disulfide bonds. IL-13 shares many activities with IL-4; this relates to a requirement for IL-4Ralpha chain for signal transduction. The biological activities of IL-13 include suppression of macrophage cytotoxic activity, upregulation of IL-1RA expression, and suppression of inflammatory cytokine expression. IL-13 induces CD23 expression on B cells and enhances CD72, and expression of class II MHC gene products. Mouse IL-13 does not display the activities on T cells and B cell stimulatory effects which IL-4 exhibits. Mouse IL-13 is active on human and mouse cells.
Specifications

Specifications

IL-13
eBio1316H
Unlabeled
Purified
Rat
50μg
Store at 2-8°C.
Monoclonal
Cytokine Neutralization
1mg/mL
aqueous buffer, no sodium azide
Interleukin-13
IgG1
RUO
Primary
Murine