IL-12/IL-23 Rat anti-Mouse, PerCP-Cy5.5, Clone: C17.8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 45-7123-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15351210

Quantity Price
1 £ 176.7 / 100µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Antigen IL-12/IL-23
Clone C17.8
Host Species Rat
Regulatory Status RUO
Format Conjugated
Gene Alias Interleukin-12, IL12 / Interleukin-23, IL23 p40
Applications Flow Cytometry (Intracellular Staining)
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL
Monoclonal or Polyclonal Monoclonal
Conjugate PerCP-Cy5.5
Isotype IgG2a
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Species Reactivity Mouse
Quantity 100μg

The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.