IL-12/IL-23 Rat anti-Mouse, PE-Cy7, Clone: C17.8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-7123-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15508636

Quantity Price
1 £ 72.77 / 25µg
Estimated Shipment date
from Supplier 04-04-2017
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Clone C17.8
Regulatory Status RUO
Isotype IgG2a
Format Conjugated
Host Species Rat
Monoclonal or Polyclonal Monoclonal
Species Reactivity Mouse
Quantity 25μg
Gene Alias Interleukin-12, IL12 / Interleukin-23, IL23 p40
Applications Flow Cytometry (Intracellular Staining)
Primary or Secondary Primary
Concentration 0.2mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen IL-12/IL-23
Conjugate PE-Cy7

The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.