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IL-12/IL-23 p40, PE, clone: C17.8, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-7123-41

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15557096

  • £56.38 / 25 tests


Estimated Shipment date
from Supplier 26-06-2018
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Description

Description

Description: The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.Applications Reported: The C17.8 antibody has been reported for use in IP, Western, ELISA, neutralization, and intracellular staining for flow cytometric analysis.Applications Tested: This C17.8 antibody has been pre-titrated and tested by intracellular flow cytometric analysis of stimulated mouse cells. This can be used at 5μL (0.25μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-12/IL-23
Monoclonal
5μl/Test
PBS with 0.2% BSA, 0.1% gelatin and 0.09% sodium azide; pH 7.2
P43432
IL12B, Il12p40, interleukin 12B, RP23-388G23.1, Il-12b, Il-12p40, p40, IL-12 p40, IL-23 subunit p40, IL12P40
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
C17.8
PE
Il12b
Conjugated
Il12b
IgG2a, kappa
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
16160
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