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IL-12/IL-23 p40, eFluor 450, clone: C17.8, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-7123-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15539806

  • £81.42 / 25µg


Estimated Shipment date
from Supplier 01-06-2018
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Description

Description

Description: The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.Applications Reported: This C17.8 antibody has been reported for use in intracellular staining followed by flow cytometric analysis.Applications Tested: This C17.8 antibody has been tested inintracellular staining and flow cytometric analysis of stimulated mouse thioglycolate-elicited peritoneal exudate cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-12/IL-23
Monoclonal
0.2mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P43432
IL12B, Il12p40, interleukin 12B, RP23-388G23.1, Il-12b, Il-12p40, p40, IL-12 p40, IL-23 subunit p40, IL12P40
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
C17.8
eFluor 450
Il12b
Conjugated
Il12b
IgG2a, kappa
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
16160
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