IL-12/IL-23 Rat anti-Mouse, Clone: C17.8, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-7123-85

500UG:ANTI-MOUSE IL-12/IL-23 P40 FUNCTIONAL

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15238767

Quantity Price
1 £ 206.0 / 500µg
Estimated Shipment date
from Supplier 20-02-2017
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Description and Specification

Specification

Applications Cytokine Neutralization
Applications Flow Cytometry (Intracellular Staining)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2a
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Antigen IL-12/IL-23
Formulation aqueous buffer, no sodium azide
Host Species Rat
Quantity 500μg
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Format Purified
Gene Alias Interleukin-12, IL12 / Interleukin-23, IL23 p40
Species Reactivity Mouse
Clone C17.8
Concentration 1mg/mL

The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.