IL-12/IL-23 Rat anti-Mouse, Clone: C17.8, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-7123-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15228767

Quantity Price
1 £ 54.42 / 50µg
EU Stock 1
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Description and Specification

Specification

Clone C17.8
Isotype IgG2a
Gene Alias Interleukin-12, IL12 / Interleukin-23, IL23 p40
Applications Cytokine Neutralization
Applications Flow Cytometry (Intracellular Staining)
Applications Immunoprecipitation
Applications Western Blotting
Concentration 1mg/mL
Conjugate Unlabeled
Formulation aqueous buffer, no sodium azide
Species Reactivity Mouse
Primary or Secondary Primary
Quantity 50μg
Host Species Rat
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Format Purified
Monoclonal or Polyclonal Monoclonal
Antigen IL-12/IL-23

The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.