IL-12/IL-23 Rat anti-Mouse, Clone: C17.8, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-7123-38

5MG Anti-Mouse IL-12/IL-23 p40 Functional Grade Purified

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15597806

Quantity Price
1 £ 1161.07 / 5mg
Estimated Shipment date
from Supplier 31-03-2017
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Description and Specification

Specification

Antigen IL-12/IL-23
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias Interleukin-12, IL12 / Interleukin-23, IL23 p40
Host Species Rat
Applications Cytokine Neutralization
Applications Flow Cytometry (Intracellular Staining)
Applications Immunoprecipitation
Applications Western Blotting
Isotype IgG2a
Quantity 5mg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Clone C17.8
Concentration 1mg/mL
Conjugate Unlabeled

The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.