IL-12/IL-23 Rat anti-Mouse, Alexa Fluor 488, Clone: C17.8, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-7123-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15530247

Quantity Price
1 £ 195.05 / 100µg
Estimated Shipment date
from Supplier 03-05-2017
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Species Reactivity Mouse
Regulatory Status RUO
Gene Alias Interleukin-12, IL12 / Interleukin-23, IL23 p40
Quantity 100μg
Isotype IgG2a
Primary or Secondary Primary
Clone C17.8
Applications Flow Cytometry (Intracellular Staining)
Conjugate Alexa Fluor 488
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Antigen IL-12/IL-23
Host Species Rat
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer

The C17.8 antibody reacts with the p40 subunit of IL-12 and IL-23. The C17.8 antibody has been found to neutralize IL-12 and IL-23 bioactivity. For specific neutralization of IL-23 only, please see clone G23-8 (anti-mouse IL-23 p19). IL-12 is a 70kDa heterodimeric cytokine composed of two covalently linked chains, p40 and p35, and is secreted by activated monocytes, macrophages, and dendritic cells. IL-23 is a heterodimer composed of the disulfide-linked p19 protein and p40 protein, expressed by activated dendritic cells.