IL-10 Rat anti-Mouse, Clone: JES5-2A5, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-7102-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298757

Quantity Price
1 £ 176.7 / 500µg
Estimated Shipment date
from Supplier 03-04-2017
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Description and Specification

Specification

Conjugate Unlabeled
Storage Requirements Store at 2-8°C.
Concentration 1mg/mL
Gene Alias Interleukin-10, IL10
Isotype IgG1
Species Reactivity Mouse
Host Species Rat
Format Purified
Primary or Secondary Primary
Clone JES5-2A5
Quantity 500μg
Antigen IL-10
Regulatory Status RUO
Applications Cytokine Neutralization
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide

The JES5-2A5 antibody reacts with mouse interleukin-10 (IL-10). The JES5-2A5 antibody is a neutralizing antibody. Mouse IL-10 is an 18kDa factor also known as Cytokine Synthesis Inhibitory Factor (CSIF). In the mouse, Th2 cells, B1 cells, macrophages, and keratinocytes are the major cell subsets that produce IL-10. IL-10 inhibits synthesis of Th1 cytokines and proliferation of T cells, and acts as a costimulatory signal for mast cells, developing thymocytes and the Th2 response.