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IL-1 beta, clone: CRM56, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-7018-85

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15287977

  • £145.49 / 500µg


EU Stock 3
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Disclaimers:

For Research Use Only.


Description

Description

Description: The CRM56 antibody reacts with human and baboon interleukin-1 beta; (IL-1 beta). IL-1 beta is a 17kDa factor secreted primarily by monocytes. IL-1 has effects on T-helper cells, inducing IL-2 secretion and expression of IL-2 receptors. IL-1 has effects on B cells, promoting cell proliferation and immunoglobulin synthesis.Applications Reported: The CRM56 antibody has been reported for use in intracellular staining for flow cytometric analysis, cytokine neutralization, and ELISA. Fluorochrome conjugated CRM56 is recommended for use in intracellular staining for flow cytometry. Functional Grade purified CRM56 (cat. 16-7018) is recommended for use in functional assays.Applications Tested: The CRM56 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of human interleukin-1 beta (IL-1 beta) in combination with the biotin CRM57 (13-7016) antibody for detection and recombinant human IL-1 beta (14-8018) as the standard. A suitable range of concentrations of this antibody for ELISA capture is 1 - 4 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 1000 pg/mL - 8 pg/mL should be included in each ELISA plate.The Functional Grade Purified CRM56 antibody has been tested for neutralization of IL-1 beta bioactivity.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

IL-1 beta
CRM56
Unconjugated
Purified
Murine
500μg
Store at 2-8°C.
Monoclonal
Flow Cytometry (Intracellular Staining)
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Interleukin-1 beta
IgG1
RUO
Primary
Human
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