IFNAR1 Mouse anti-Mouse, PE, Clone: MAR1-5A3, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 12-5945-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionInterferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.