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IEM 1460, Tocris Bioscience™

Open-channel blocker of AMPA currents; selective for non-GluA2-containing receptors

Brand:  Tocris (Bio-Techne) 163650

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13429843

  • £469.16 / 50mg

Estimated Shipment
14-09-2020

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Description

Description

Voltage-dependent open-channel blocker of AMPA receptors. Selective for GluR2 subunit-lacking (Ca2+-permeable) receptors over GluA2-containing receptors (IC50 values are 2.6 and 1102 μM, respectively). Selectively blocks fast spiking interneuron but not medium spiny projection neuron in mouse striatum. Also blocks NMDA receptor-mediated currents. Anticonvulsant in vivo.
Specifications

Chemical Identifiers

121034-89-7
454.335
tocris-1636, 5-1-adamantylmethylamino pentyl-trimethylazanium bromide hydrobromide, 5-adamantan-1-ylmethyl amino pentyl trimethylazanium hydrobromide bromide, n,n,h,-trimethyl-5-tricyclo 3.3.1.13,7 dec-1-ylmethyl amino-1-pentanaminiumbromide hydrobromide
5-(1-adamantylmethylamino)pentyl-trimethylazanium;bromide;hydrobromide
C19H38Br2N2
CQTDZUSQSTUZDA-UHFFFAOYSA-M
6604954
C[N+](C)(C)CCCCCNCC12CC3CC(C1)CC(C3)C2.Br.[Br-]

Specifications

IEM 1460
121034-89-7
tocris-1636, 5-1-adamantylmethylamino pentyl-trimethylazanium bromide hydrobromide, 5-adamantan-1-ylmethyl amino pentyl trimethylazanium hydrobromide bromide, n,n,h,-trimethyl-5-tricyclo 3.3.1.13,7 dec-1-ylmethyl amino-1-pentanaminiumbromide hydrobromide
C[N+](C)(C)CCCCCNCC12CC3CC(C1)CC(C3)C2.Br.[Br-]
454.335
454.33
50mg
C19H38Br2N2
CQTDZUSQSTUZDA-UHFFFAOYSA-M
5-(1-adamantylmethylamino)pentyl-trimethylazanium;bromide;hydrobromide
6604954
>98%
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