IDO Rat anti-Mouse, PerCP-eFluor 710, Clone: mIDO-48, eBioscience™

Rat Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 46-9473-80

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15559416

Quantity Price
1 £ 103.33 / 25µg
EU Stock 2
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Description and Specification

Specification

Isotype IgG2b
Applications Flow Cytometry (Intracellular Staining)
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Antigen IDO
Concentration 0.2mg/mL
Gene Alias Indoleamine 2,3-dioxygenase 1
Primary or Secondary Primary
Species Reactivity Mouse
Monoclonal or Polyclonal Monoclonal
Conjugate PerCP-eFluor 710
Host Species Rat
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Quantity 25μg
Clone mIDO-48
Regulatory Status RUO

The monoclonal antibody mIDO-48 reacts with mouse indoleamine 2,3-dioxygenase 1(IDO1). IDO1 is an enzyme expressed intracellularly by dendritic cells, interferon gamma activated macrophages, epithelial cells, vascular endothelium and tumor cells. This enzyme catalyzes tryptophan into kynurenine metabolites. The reduction of tryptophan and the introduction of kynurenine metabolites in the microenvironment of IDO-expressing cells suppress T cell proliferation and promote the activation and induction of regulatory T cells.