IDO Mouse anti-Human, PE-Cy7, Clone: eyedio, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-9477-41

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15528666

Quantity Price
1 £ 78.88 / 25 tests
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Concentration 5μL (0.06μg)/test
Species Reactivity Human
Applications Flow Cytometry (Intracellular Staining)
Quantity 25 tests
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Isotype IgG1
Gene Alias Indoleamine-2,3-dioxygenase
Host Species Mouse
Conjugate PE-Cy7
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen IDO
Clone eyedio

This eyedio monoclonal antibody reacts with human indoleamine-2,3-dioxygenase (IDO, INDO, IDO1), an intracellular enzyme that catalyzes the degradation of tryptophan to kynurenines. IDO is expressed in a wide variety of tissues and cells, including macrophages, plasmacytoid dendritic cells, and several cell lines. IDO can be induced in many different cell types by IFN gamma or other inflammatory stimuli. Expression of IDO in antigen presenting cells and tumors is thought to mediate immune suppression through depletion of this essential amino acid and/or by the creation of tryptophan metabolites that cause apoptosis of T cells and induction of regulatory T cells.