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IDO Mouse anti-Human, eFluor 660, Clone: V1NC3IDO, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-9750-80

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15540117

  • £61.70 / 25µg


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For Research Use Only.


Description

Description

The monoclonal antibody V1NC3IDO recognizes human IDO. IDO (indoleamine-2,3-dioxygenase, INDO, IDO1) is an intracellular enzyme that catalyzes the degradation of tryptophan to kynurenines. IDO is expressed in a wide variety of tissues and cells, including macrophages, plasmacytoid dendritic cells, and several cell lines. IDO can be induced in many different cell types by IFN gamma or other inflammatory stimuli. Expression of IDO in antigen presenting cells and tumors is thought to mediate immune suppression through depletion of this essential amino acid and/or by the creation of tryptophan metabolites that cause apoptosis of T cells and induction of regulatory T cells.

This V1NC3IDO antibody reacts with IDO1 and does not cross react with IDO2.
Specifications

Specifications

IDO
V1NC3IDO
eFluor 660
Conjugated
Murine
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Immunohistochemistry (Formalin/Paraffin)
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Indoleamine-2,3-dioxygenase
IgG2b
RUO
Primary
Human
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