IDO Mouse anti-Human, Clone: V1NC3IDO, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9750-80

25UG Anti-Human IDO Purified

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15587626

Quantity Price
1 £ 73.6 / 25µg
Estimated Shipment date
from Supplier 13-12-2016
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Description and Specification

Specification

Antigen IDO
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Microscopy
Clone V1NC3IDO
Concentration 0.5mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias Indoleamine-2,3-dioxygenase
Host Species Mouse
Isotype IgG2b
Quantity 25μg
Regulatory Status RUO
Species Reactivity Human
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

The monoclonal antibody V1NC3IDO recognizes human IDO. IDO (indoleamine-2,3-dioxygenase, INDO, IDO1) is an intracellular enzyme that catalyzes the degradation of tryptophan to kynurenines. IDO is expressed in a wide variety of tissues and cells, including macrophages, plasmacytoid dendritic cells, and several cell lines. IDO can be induced in many different cell types by IFN gamma or other inflammatory stimuli. Expression of IDO in antigen presenting cells and tumors is thought to mediate immune suppression through depletion of this essential amino acid and/or by the creation of tryptophan metabolites that cause apoptosis of T cells and induction of regulatory T cells.

This V1NC3IDO antibody reacts with IDO1 and does not cross react with IDO2.