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ICA 069673, Tocris Bioscience™

KV7.2/KV7.3 channel opener

Brand:  RD Systems (Bio-Techne) 4305/10

Code : Z1

Additional Details : Weight : 0.00010kg

Quantity 10mg

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Product Code. 13464524

  • £157.08 / 10mg


Estimated Shipment
29-10-2018
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Description

Description

Selective KV7.2/KV7.3 (KCNQ2/3) channel opener (EC50 = 0.69μM). Exhibits 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV7.5, with no measurable activity over a panel of cardiac ion channels. Hyperpolarizes resting membrane potential and inhibits spontaneous action potentials in guinea pig detrusor muscle (DSM) isolated cells. Orally active in animal models of epilepsy.
Specifications

Chemical Identifiers

582323-16-8
269.636
n-2-chloropyrimidin-5-yl-3,4-difluorobenzamide, ica hplc, n-2-chloro-5-pyrimidinyl-3,4-difluorobenzamide, n-2-chloro-pyrimidin-5-yl-3,4-difluoro-benzamide
N-(2-chloropyrimidin-5-yl)-3,4-difluorobenzamide
C11H6ClF2N3O
IIBSHMFXVWTQSJ-UHFFFAOYSA-N
10149311
C1=CC(=C(C=C1C(=O)NC2=CN=C(N=C2)Cl)F)F

Specifications

ICA 069673
582323-16-8
n-2-chloropyrimidin-5-yl-3,4-difluorobenzamide, ica hplc, n-2-chloro-5-pyrimidinyl-3,4-difluorobenzamide, n-2-chloro-pyrimidin-5-yl-3,4-difluoro-benzamide
C1=CC(=C(C=C1C(=O)NC2=CN=C(N=C2)Cl)F)F
269.636
269.63
10mg
C11H6ClF2N3O
IIBSHMFXVWTQSJ-UHFFFAOYSA-N
N-(2-chloropyrimidin-5-yl)-3,4-difluorobenzamide
10149311
>99%
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