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I kappa B zeta Rat anti-Mouse, Clone: LK2NAP, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-6801-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15217957

  • £152.25 / 100µg


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For Research Use Only.


Description

Description

The LK2NAP monoclonal antibody reacts with mouse IkB zeta (INAP, MAIL). IkBz is a member of the IkB family of cytoplasmic proteins and transcription factors and also shares structural homology with Bcl-3. It is induced in monocytes, macrophages and B cells in response to TLR and IL-1R signaling. In NK cells, IkBz is rapidly upregulated in response to IL-12 and IL-18 and is necessary for production of IFN gamma. In T cells, IkBz is not necessary for IFN gamma and IL-4 production by Th1 and Th2 cells, respectively. However in Th17 cells, IkBz acts in concert with RORa and RORgt to upregulate IL-17A, IL-17F, IL-21, IL-22 and IL-23R expression.
Specifications

Specifications

I kappa B zeta
LK2NAP
Unlabeled
Purified
Rat
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
NF-kappa-B inhibitor zeta, Nfkbiz
IgG2a
RUO
Primary
Murine