IkB zeta, clone: LK2NAP, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-6801-82
Code : Z2
Additional Details : Weight : 0.01000kg
DescriptionDescription: The LK2NAP monoclonal antibody reacts with mouse IkB zeta (INAP, MAIL). IkBz is a member of the IkB family of cytoplasmic proteins and transcription factors and also shares structural homology with Bcl-3. It is induced in monocytes, macrophages and B cells in response to TLR and IL-1R signaling. In NK cells, IkBz is rapidly upregulated in response to IL-12 and IL-18 and is necessary for production of IFN gamma. In T cells, IkBz is not necessary for IFN gamma and IL-4 production by Th1 and Th2 cells, respectively. However in Th17 cells, IkBz acts in concert with RORa and RORgt to upregulate IL-17A, IL-17F, IL-21, IL-22 and IL-23R expression.Applications Reported: This LK2NAP antibody has been reported for use in western blotting.Applications Tested: This LK2NAP antibody has been tested by western blotting on reduced lysates at > 1 ug/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
|I kappa B zeta|
|Store at 2-8°C.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|NF-kappa-B inhibitor zeta, Nfkbiz|
For Research Use Only.