missing translation for 'onlineSavingsMsg'
Learn More

Abnova™ Human WNT1 (P04628, 343 amino acids) Partial Recombinant Protein

Used for Func, SDS-PAGE

Brand:  Abnova™ P4134.10ug

Additional Details : Weight : 0.00010kg

Product Code. 16282070

This item is currently unavailable or has been discontinued.
View the product page for possible alternatives.


Description

Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. [provided by RefSeq]

Specifications

Specifications

P04628
Lyophilized
38.4kDa
Escherichia coli expression system
10 ug
RUO
INT1
WNT1
E. coli
None
Lyophilized
Functional Study, SDS-PAGE
7471
WNT1 (Human) Recombinant Protein
SDS-PAGE Stained with Coomassie Blue
Store at -20°C on dry atmosphere. After reconstitution with sterilized water, store at -20°C. Aliquot to avoid repeated freezing and thawing.
<0.1ng/μg
WNT1
The ED50 was determined by its ability to enhance BMP-2 induced alkaline phosphatase production by murine ATDC5 cells. The expected ED50 for this effect is 1.5-2.5ng/mL in the presence of 200ng/mL of human BMP-2.
Recombinant
Escherichia coli expression system
≥98% by SDS-PAGE and HPLC
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers