missing translation for 'onlineSavingsMsg'
Learn More

Invitrogen™ TNF beta Human ELISA Kit

For the quantitative detection of human TNF-beta.

Brand:  Invitrogen™ BMS202

Code : NEW

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15561507

  • £377.00 / 96 tests


EU Stock 4
Add to basket

Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human TNF-beta
HRP-Conjugate anti-human TNF-beta monoclonal antibody
Human TNF-beta Standard concentrate, 1ng/mL upon dilution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Adhesive Films

Description

Description

Tumor Necrosis Factor (TNF) was originally discovered as a serum protein with necrotizing effects on certain transplantable mouse tumors in vivo and cytotoxic effects against some transformed cells in vitro. The TNF family consists of two proteins designated TNF-alpha, also called cachectin, and TNF-beta, also called lymphotoxin. Soluble TNF-beta is a T-cell derived glycoprotein of 25 kD mainly produced by activated lymphocytes. TNF-beta is 28 % structurally homologous with the macrophage produced non-glycoprotein TNF-alpha. TNF-beta is induced in an antigen-specific MHC restricted fashion from class I and class II restricted T cells. Viral infection is also associated with TNF-beta production by lymphoid cells. TNF-beta has several effects on target cells including killing, growth stimulation, induction of adhesion molecule (ICAM-1) expression, and induction of differentiation. The mechanisms of TNF-beta effects involve receptor binding and internalization and several sequelae including changes in prostaglandins and chromosome integrity. TNF-beta participates in tumor immunity, and it has been reported to inhibit carcinogenesis as well as growth of some tumors in vivo.
Specifications

Specifications

P01374
HRP
4049
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, HRP-conjugated Detection Antibody, Wash Buffer, Chromogen, Stop Solution, Controls, Adhesive Plate Covers
RUO
100 μL
2°C to 8°C
4 hr. 10 min.
LT,TNFB,TNFSF1,TNLG1E
10.2%
HRP
Human
15.6-1,000 pg/mL
ELISA
Colorimetric Microplate Reader
ELISA Kit
4.6 pg/mL
Plasma, 100 μL|Serum, 100 μL|Supernatant, 100 μL
1 hr. 20 min.
Human
Lymphotoxin-alpha, TNF superfamily member 1
8%
96 Tests
Supernatant
Videos
Documents

For Research Use Only