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Invitrogen™ TNF beta Human ELISA Kit

For the quantitative detection of human TNF-beta.

Brand:  Invitrogen™ BMS202

301.60 GBP valid until 2020-12-18
Use promo code "14718" to get your promotional price.



Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15561507

  • £377.00 / 96 tests


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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human TNF-beta
HRP-Conjugate anti-human TNF-beta monoclonal antibody
Human TNF-beta Standard concentrate, 1ng/mL upon dilution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Adhesive Films

Description

Description

Tumor Necrosis Factor (TNF) was originally discovered as a serum protein with necrotizing effects on certain transplantable mouse tumors in vivo and cytotoxic effects against some transformed cells in vitro. The TNF family consists of two proteins designated TNF-alpha, also called cachectin, and TNF-beta, also called lymphotoxin. Soluble TNF-beta is a T-cell derived glycoprotein of 25 kD mainly produced by activated lymphocytes. TNF-beta is 28 % structurally homologous with the macrophage produced non-glycoprotein TNF-alpha. TNF-beta is induced in an antigen-specific MHC restricted fashion from class I and class II restricted T cells. Viral infection is also associated with TNF-beta production by lymphoid cells. TNF-beta has several effects on target cells including killing, growth stimulation, induction of adhesion molecule (ICAM-1) expression, and induction of differentiation. The mechanisms of TNF-beta effects involve receptor binding and internalization and several sequelae including changes in prostaglandins and chromosome integrity. TNF-beta participates in tumor immunity, and it has been reported to inhibit carcinogenesis as well as growth of some tumors in vivo.
Specifications

Specifications

P01374
HRP
4049
ELISA Kit
4.6 pg/mL
Plasma, 100 μL|Serum, 100 μL|Supernatant, 100 μL
1 hr. 20 min.
Human
Lymphotoxin-alpha, TNF superfamily member 1
8%
Human
HRP
15.6-1,000 pg/mL
ELISA
Pre-coated 96 well plate, Standard, Sample Diluent, Assay Buffer concentrate, HRP-conjugated Detection Antibody, Wash Buffer, Chromogen, Stop Solution, Controls, Adhesive Plate Covers
RUO
100 μL
2°C to 8°C
4 hr. 10 min.
LT,TNFB,TNFSF1,TNLG1E
10.2%
96 Tests
Supernatant
Colorimetric Microplate Reader
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