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eBioscience™ Human CXCL10 (IP-10), Recombinant Protein, Carrier-Free

Human Recombinant Protein

Brand:  Affymetrix eBioscience 34-8967-85

Code : NEW

Additional Details : Weight : 0.09500kg

Product Code. 15598836

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Description

Description

CXCL10, also known as IP-10 (Interferon Inducible Protein-10), is a member of the CXC family of chemokines. It is secreted by monocytes, epithelial cells, and endothelial cells in response to IFN gamma or other pro-inflammatory cytokines and stimuli. CXCL10 signaling is mediated by the g protein-coupled receptor CXCR3, which is expressed on activated T cells and plays an important role in directing the migration of T cells, especially during Th1 responses. In addition to its role as a chemoattractant, CXCL10 is also a potent inhibitor of angiogenesis and exhibits antitumor activity.
Specifications

Specifications

NM_001565
Cytokine Bioassays
8.8kDa
SDS-PAGE
500μg
Store at less than or equal to -70°C.
E. coli-expressed amino acids Val22-Pro98, accession number NM_001565
Interferon Inducible Protein 10
Recombinant Protein, Carrier-Free
Human
0.5mg/mL
Sterile liquid; phosphate-buffered saline, pH 7.2
CXCL10 (IP-10)
>97%
E. coli
RUO
Less than 0.01ng/μg cytokine as determined by the LAL assay.
The bioactivity of this protein was determined by transmigration assay of human T lymphocytes, with maximum chemotaxis observed at 100-200ng/mL.
Unlabeled
Yes
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